Job Description

Director, Global Value Access & Strategy, AMKD

Location: Boston, MA (3 days onsite, 2 days remote weekly)

Vertex operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF) as well as Casgevy, a gene therapy for sickle cell disease and beta-thalassemia. Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Pain, APOL-1 mediated kidney disease (AMKD), and cell therapies for Type 1 diabetes, among others.

Overview:

Market Access is a key commercial function that ensures transformative Vertex therapies are appropriately funded and ultimately make it into the hands of the patients around the world. The GVAS (Global Value & Access Strategy) team works cross-functionally and across regions to ensure the payer view is represented in commercial and development plans across the lifecycle. We are driven by a desire to deliver groundbreaking pricing & reimbursement solutions to allow our medicines to reach patients faster than ever before.

The Director, GVAS role will serve as Market Access Lead for our APOL-1 mediated kidney disease (AMKD) portfolio, with a focus on lead asset inaxaplin. Pipeline products for AMKD are in development to treat chronic kidney diseases in patients with APOL-1 genetic risk alleles. The individual will be responsible for leading the development of Global Market Access strategies, as well as co-lead for the Global Commercial Team. The role reports to Sr Director, Genetic Kidney Disease lead.

Key Responsibilities:

• Responsible for Global payer strategic planning to support value and access optimization for lead AMKD asset inaxaplin

  • Lead development of Market Access strategies and core Global P&R deliverables operating within the cross-functional, cross-regional commercialization process

    • Responsible for Global payer strategic planning to support value and access optimization; lead development of Global Payer Plan which integrates value evidence generation, strategic pricing, value communications, stakeholder engagement to support successful reimbursement and pricing

  • Accountable for ensuring the market access and payer perspective is reflected in cross-functional strategies (e.g. commercial, product development, regulatory affairs)

  • Ensure evidence prioritization required to capture value, support a differentiated target product profile (TPP), and ensure local pricing and access

  • Support strategies with deep functional knowledge, in-depth market research, environmental data & analogs

  • Inform financial forecasts

  • Partner with Health Economics & Outcomes Research (HEOR), Real-World Evidence (RWE) and Global Marketing to ensure robust value proposition and integrated evidence plans are optimized to support global market access and reimbursement

• Co-lead AMKD Global Commercial Team (with Global Marketing) and work cross-functionally and cross-regionally to develop optimal commercial strategies

  • The Global Commercial Team facilitates development of a commercial strategy in order to maximize the lifetime value of the asset globally; is the primary hub for alignment and input into the Disease Strategy Team

  • This role should ensure collaboration and drive alignment across Global Commercial Team and leadership to integrate market access strategy and ensure resourcing for commercial success

• Support P&MA capability building and thought leadership projects that advance knowledge of and readiness for the rapidly evolving Global payer environment

• Maintain industry awareness and proactively address changes in market trends, competition, product acceptance and new product releases and adjust Market Access plans accordingly

• Collaborate closely with HEOR, International P&R, Corporate Affairs, US Market Access, Countries, Marketing and Clinical Development counterparts to ensure value and access optimization

Education and Experience:

• BA/BS in field of study requiring quantitative analysis; advanced degree preferred

• 8+ years of direct biotechnology / pharmaceutical industry experience and/or payer experience

• Deep working knowledge of both US and ex-US healthcare systems required; experience in comparable Global role considered a plus

• Experience in leading cross-functional teams required

• Experience in specialty and/or rare disease access models preferred

• Demonstrated ability to think strategically and make sound pricing and market access recommendations

• Entrepreneurial, energetic, dynamic, enthusiastic, decisive, and self-motivated; possesses a sense of urgency with the ability and strong desire to "make things happen"

• Strong practical, quantitative and analytical skills combined with a sound understanding of how to successfully apply pricing & reimbursement / HEOR principles to support Vertex

• General experience in commercialization and drug development

• Exhibits outstanding written and oral communication skills, including the ability to effectively write and deliver presentations to professionals at all levels within Vertex

• Demonstrated relationship building at all levels of the organization and across geographies

• Recognized as a team player with excellent interpersonal skills who is flexible and reliable

• Displays sound ethics and a fit for Vertex’s core values

#LI-KM3

Flex Designation:

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com